Humulin 70/30 (human insulin isophane suspension and human insulin injection) is a mixture of 70% human insulin isophane, intermediate-acting human insulin, and 30% human insulin, short-acting human insulin. Human insulin is produced by recombinant DNA technology utilizing a non-pathogenic laboratory strain of Escherichia coli. Humulin 70/30 is a suspension of crystals made from combining human insulin and protamine sulfate under appropriate conditions for crystal formation and mixing with human insulin injection.
This medication is a white and cloudy suspension that contains human insulin isophane suspension (NPH) and human insulin injection (regular) for subcutaneous use. Each milliliter contains 100 units of human insulin, 0.24 mg of protamine sulfate, 16 mg of glycerin, 3.78 mg of dibasic sodium phosphate, 1.6 mg of metacresol, 0.65 mg of phenol, zinc oxide content adjusted to provide 0.025 mg zinc ion, and Water for Injection.
This medication is injected under the skin. It should not be injected into a vein or muscle. Doses of insulin are measured in units. U-100 insulins, including Humulin 70/30, contain 100 units/mL. Humulin 70/30 should be given subcutaneously approximately 30-45 minutes before a meal. Humulin 70/30 also comes in cartridges.